Subjective and objective cognitive impairment in patients with obstructive sleep apnea

Background Obstructive sleep apnea (OSA) is associated with cognitive impairment (CI). We aimed to study subjective complaint (SCC) and objective scores, its relation polysomnography (PSG) parameters, in patients suspected of OSA. Method Patients OSA who were scheduled for PSG recruited. Cognition was assessed by the Montreal Cognitive Assessment (MoCA) Color Trails Test (CTT). The Memory index score (MIS) also calculated from MoCA. presence SCC asking directly using Change Index rated self (CCI-S) or informants (CCI-I). severe dementia excluded. Result Among 258 an age 61.46±7.05 years, 51.2% are female. mean MoCA 23.89±3.89. Based on PSG, classified as having no mild (20.1%), moderate (28.3%), (51.6%). tests, had a higher proportion (64.1%) but less (38.3%) than CCI-S CCI-I scores significantly correlated each other (r = 0.238, p 0.019) not nor CTT-time. Objective tests number comorbidities several i.e., total time, onset latency, wake after onset, stages, O2 saturation, time spent SaO2 under 90% (all p<0.05). Meanwhile, any parameters. However, self-report Thai-Geriatric Depression Scale Epworth Sleepiness 0.388 0.262, respectively, <0.001). Thirty CI followed-up CPAP treatment 12.2 months showed significant improvement MIS CTT CCI scores. Conclusion Most impairment, found more stage Several parameters could have benefit treatment.